The first European university was founded in Bologna, Italy in 1119. Universities were established in Siena in 1203 and Vincenza in 1204. By the end of the 13th century, universities had been established in Paris, Bologna, Padua, Ghent, Oxford, Cambridge. These were major sites for the institution of a new relationship to books, to learning, and to the Word of God.
These were important institutions because, prior to the advent and rise of the university, learning in Europe had been dominated by the Roman Catholic Church. With the advent of the secular university, students were no longer studying for the clergy. While some students were still from the aristocracy, others were the people who lived in the cities where the universities were located, who had time to attend lectures and take part in the intellectual life of the university.
In many cases, the university consisted of lecturers who lived in the town. If a group of people wanted a class they would go hire a lecturer and pay him to give a series of lectures.
The shift from a religious focus on the next world and the worship of God to a secular focus on the present world and an interest in the natural world. Merchants have different interests from priests.
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These new centers of learning created new demands for books. These students didn't have access to the books locked away in monastaries. so they had no access to books. With the rise of this new form of learning, they needed access to new kinds of books not readily available - e.g. non-religious texts.
So the university created a system of demand for books as well as a system for the use of books in ways not used with religious texts.
This effect of the university on book production is what Febvre and Martin take as more revolutionary than the advent of the printing press.
Two new kinds of institutions grew up around the universities to provide for that demand: stationers and book copiers. These folks provided paper and libraries of text books that had been carefully studied and compared to other books for accuracy. They made these books available for copying by students. When a student needed a text for a class, he would go down to the stationers and copy them - by hand. Or he could pay a book copier to copy the book for him.
There are several problems with this mode of book production. The most obvious is that inaccuracies get introduced as the book gets copied.
Second, stationers may try to get accurate copies of the texts, but they have no way to really know how accurate their copies were.
The combination of these factors lead to a compounding of inaccuracies in the texts people used. Mistakes get compounded as copiers get tired, bored, or simply pass along mistakes they don't catch.
But this also created a snowball effect that led to more demand for books well in advance of the advent of the printing press's ability to meet that demand.
Books needed were not just religious texts so much as books on more secular subjects:
The first book on Surgery, the Chirurgi Magna was written in 1363.